All properties are independently selected. We may earn a commission from bookings, but this does not affect our recommendations.

Affiliate disclosure

All properties are independently selected. We may earn a commission from bookings, but this does not affect our recommendations.

Birmingham hotels
All articles
Best Hotels in Five Points South, Birmingham

The Birmingham Journal

Best Hotels in Five Points South, Birmingham

Your essential guide to Five Points South hotels, curated for every travel style and budget.

Etienne
by Etienne Girard
Verified Expert
Updated Jan 30, 2026
10 min read
494 visits

Top Places to Stay in Five Points South, On Map

All hotels were sorted by rating and number of reviews

Hotels featured in this article
1. Hilton Birmingham Downtown At Uab
2. Residence Inn By Marriott Birmingham Downtown Uab
3. Home2 Suites By Hilton Birmingham Downtown
4. Hilton Garden Inn Downtown Birmingham
5. The Painted Lady
6. Courtyard By Marriott Birmingham Downtown At Uab
7. Hotel Indigo - Birmingham Five Points S - Uab By Ihg
8. Springhill Suites By Marriott Birmingham Downtown At Uab
9. Homewood Suites By Hilton Birmingham Downtown Near Uab
10. Hassinger Daniels Guest House
11. Cobb Lane Bed And Breakfast

We handpicked hotels in Five Points South, Birmingham, focusing on prime locations, unique design, and exceptional reviews. Offering multiple price points, our selection accommodates various traveler preferences.

In this neighborhood, you'll find a rich culinary scene, vibrant street art, and easy access to the famous Birmingham Zoo, which is just 3 km away. The area suits young professionals, families, and tourists eager to experience urban charm.

Why Stay in Five Points South?

Five Points South appeals to diverse visitors due to its proximity to downtown Birmingham, only a 10-minute drive away. Shopping at local favorites such as Pizitz Food Hall and appreciating the architectural beauty of the historic Alabama Theatre make it attractive to all.

Travelers can enjoy nearby attractions like the Birmingham Museum of Art and the historic Vulcan Park. Highly-rated hotels like the Homewood Suites provide comfort, while Cafè Dupont serves up local flavors undeniable in quality.

Is Five Points South Safe?

Five Points South is generally safe with a noticeable police presence, helping maintain a secure environment. Visitors should stick to well-lit streets, such as 20th Street South, after dark. Although crime rates are low, occasional pickpocketing incidents can occur near busy restaurants like Highlands Bar and Grill. Staying alert and avoiding quiet alleys is advisable.

Pet-friendly Hotels in Five Points South, Birmingham

  • 2 km from center
    -
    Hilton Birmingham Downtown At Uab Hilton Birmingham Downtown At Uab Hilton Birmingham Downtown At Uab Hilton Birmingham Downtown At Uab Hilton Birmingham Downtown At Uab

    That was just a preview — check out all hotel photos.

    Best by event space
    1/1

    MAIN FEATURES

    • Extensive event facilities accommodating up to 900 attendees.
    • Unique local dining experiences full of Southern flair.
    • Complimentary shuttle service within one mile for guests.
    Elegance meets convenience at Hilton Birmingham Downtown at UAB. Nestled close to the renowned UAB Medical Campus, this hotel features spacious guest rooms and southern restaurants that delight. An extensive event space accommodates significant gatherings. Just a short stroll to vibrant attractions like the Birmingham Zoo, it's a prime urban retreat for business and leisure.

    Just a few rooms left at the best rate! 

    $114-$240 per night

    Rates from verified hotel providers

  • 2 km from center
    -
    Residence Inn By Marriott Birmingham Downtown Uab Residence Inn By Marriott Birmingham Downtown Uab Residence Inn By Marriott Birmingham Downtown Uab Residence Inn By Marriott Birmingham Downtown Uab Residence Inn By Marriott Birmingham Downtown Uab

    That was just a preview — check out all hotel photos.

    Best by family-friendly amenities
    1/1

    MAIN FEATURES

    • Spacious suites with kitchen facilities perfect for extended stays.
    • Complimentary evening social hour fostering community vibes.
    • Pet-friendly policy that welcomes furry companions.
    Residence Inn By Marriott Birmingham Downtown UAB offers spacious suites with fully equipped kitchens, making it a favorite among families and business travelers. A seasonal outdoor pool and fitness center enhance the experience. Nearby, attractions like Vulcan Park and Birmingham Zoo await, providing endless exploration for leisure seekers right outside your door.

    Rooms filling fast – secure the best rate! 

    $124-$247 per night

    Rates from verified hotel providers

  • 933 m from center
    -
    Home2 Suites By Hilton Birmingham Downtown Home2 Suites By Hilton Birmingham Downtown Home2 Suites By Hilton Birmingham Downtown Home2 Suites By Hilton Birmingham Downtown Home2 Suites By Hilton Birmingham Downtown

    That was just a preview — check out all hotel photos.

    Best for urban explorers
    1/1

    MAIN FEATURES

    • 24-hour fitness center with a Peloton bike for active guests.
    • Saltwater swimming pool ideal for relaxation and family fun.
    • Complimentary breakfast with a diverse selection for every taste.
    Chic and flexible, Home2 Suites By Hilton Birmingham Downtown caters to both family stays and business visits. With spacious rooms, each featuring kitchenettes, this hotel thrives on community atmosphere, highlighted by a vibrant breakfast setup. Its location offers quick access to top attractions like the Birmingham Civil Rights Institute, making it a solid choice for urban adventurers.

    Hurry – almost gone at this price! 

    $149-$216 per night

    Rates from verified hotel providers

  • 999 m from center
    -
    Hilton Garden Inn Downtown Birmingham Hilton Garden Inn Downtown Birmingham Hilton Garden Inn Downtown Birmingham Hilton Garden Inn Downtown Birmingham Hilton Garden Inn Downtown Birmingham

    That was just a preview — check out all hotel photos.

    Best for convenient dining
    1/1

    MAIN FEATURES

    • On-site restaurant offering cooked-to-order meals emphasizing freshness.
    • Seasonal outdoor pool for relaxation during warmer months.
    • Pet-friendly accommodations with a welcoming policy for furry guests.
    Modern amenities meet Southern hospitality at Hilton Garden Inn Downtown Birmingham. This hotel boasts spacious conference areas and an on-site restaurant serving cooked-to-order meals. Enjoy proximity to local attractions like McWane Center while relaxing in a seasonal outdoor pool, catering to both leisure travelers and business guests in vibrant Five Points South.

    Just a few rooms left at the best rate! 

    $489-$643 per night

    Rates from verified hotel providers

  • 5. The Painted Lady

    9.0 Superb
    75 reviews
    1 km from center
    -
    The Painted Lady The Painted Lady The Painted Lady The Painted Lady The Painted Lady

    That was just a preview — check out all hotel photos.

    Best for boutique charm
    1/1

    MAIN FEATURES

    • Cozy coffee shop on-site providing artisanal brews.
    • Charming boutique atmosphere distinct from traditional hotels.
    • Smoke-free environment enhancing the overall guest experience.
    The Painted Lady exudes charm in Birmingham's Five Points South. This boutique hotel is renowned for its smoke-free environment, free breakfast, and spacious, elegantly decorated rooms. Positioned just minutes from cultural venues like the Birmingham Botanical Gardens, it offers unique contemporary comforts in a historic setting, making it ideal for business travelers and leisure enthusiasts alike.

    Rooms filling fast – secure the best rate! 

    $192-$192 per night

    Rates from verified hotel providers

Luxury Accommodations in Five Points South, Birmingham

  • 1 km from center
    -
    Courtyard By Marriott Birmingham Downtown At Uab Courtyard By Marriott Birmingham Downtown At Uab Courtyard By Marriott Birmingham Downtown At Uab Courtyard By Marriott Birmingham Downtown At Uab Courtyard By Marriott Birmingham Downtown At Uab

    That was just a preview — check out all hotel photos.

    Best for medical visits
    1/1

    MAIN FEATURES

    • Skybridge access to UAB Hospital for hospital visits and convenience.
    • Modern Bistro dining experience with locally inspired dishes.
    • Flexible reservation policies tailored for family needs during medical visits.
    Courtyard By Marriott Birmingham Downtown At UAB offers contemporary comfort directly connected to UAB Hospital via a skybridge. Families and business travelers appreciate the on-site Bistro, serving delightful American cuisine, and the fitness center equipped for a productive stay. Located near Five Points South's vibrant dining scene, it's perfect for combining work and pleasure.

    Just a few rooms left at the best rate! 

    $139-$317 per night

    Rates from verified hotel providers

  • 2 km from center
    -
    Hotel Indigo - Birmingham Five Points S - Uab By Ihg Hotel Indigo - Birmingham Five Points S - Uab By Ihg Hotel Indigo - Birmingham Five Points S - Uab By Ihg Hotel Indigo - Birmingham Five Points S - Uab By Ihg Hotel Indigo - Birmingham Five Points S - Uab By Ihg

    That was just a preview — check out all hotel photos.

    Best for cultural immersion
    1/1

    MAIN FEATURES

    • Historic building featuring a captivating Art Deco design capturing local culture.
    • RX Lounge offers curated southern cuisine and craft cocktails in style.
    • Sleek meeting spaces equipped with audiovisual support for seamless events.
    With a historic Art Deco charm, Hotel Indigo offers an inviting retreat in Birmingham's cultural hub. Guests can savor artisanal delights at the RX Lounge while indulging in stunning skyline views. Ideal for business or leisure travelers, this unique hotel's proximity to Birmingham attractions, including museums and nightlife, makes it a kinetic urban spot.

    Hurry – almost gone at this price! 

    $102-$162 per night

    Rates from verified hotel providers

  • 1 km from center
    -
    Springhill Suites By Marriott Birmingham Downtown At Uab Springhill Suites By Marriott Birmingham Downtown At Uab Springhill Suites By Marriott Birmingham Downtown At Uab Springhill Suites By Marriott Birmingham Downtown At Uab Springhill Suites By Marriott Birmingham Downtown At Uab

    That was just a preview — check out all hotel photos.

    Best by family suites
    1/1

    MAIN FEATURES

    • Unique suite configurations designed for families and group gatherings.
    • Complimentary shuttle service to local attractions for extra convenience.
    • On-site barbecue facilities inviting casual dining and mingling.
    Springhill Suites By Marriott Birmingham Downtown seamlessly combines convenience with spacious comfort. This all-suites hotel provides a family-friendly atmosphere and unique suite configurations ideal for larger groups. Just moments from local attractions, it features engaging common areas, an indoor pool, and complimentary breakfast to fuel your adventures.

    Rooms filling fast – secure the best rate! 

    $170-$257 per night

    Rates from verified hotel providers

  • 2 km from center
    -
    Homewood Suites By Hilton Birmingham Downtown Near Uab Homewood Suites By Hilton Birmingham Downtown Near Uab Homewood Suites By Hilton Birmingham Downtown Near Uab Homewood Suites By Hilton Birmingham Downtown Near Uab Homewood Suites By Hilton Birmingham Downtown Near Uab

    That was just a preview — check out all hotel photos.

    Best for extended stays
    1/1

    MAIN FEATURES

    • All-suites design with full kitchens providing home-like comfort.
    • Complimentary evening social gathering fostering community among guests.
    • Indoor heated swimming pool available year-round for family fun.
    Homewood Suites By Hilton Birmingham Downtown offers an inviting all-suites experience, perfect for extended stays. Each suite features a full kitchen and a spacious living area, ideal for families and business travelers alike. Located near the University of Alabama, it provides a warm atmosphere complemented by complimentary evening socials and an indoor pool.

    Hurry – almost gone at this price! 

    $146-$251 per night

    Rates from verified hotel providers

  • 10. Hassinger Daniels Guest House

    8.0 Very Good
    20 reviews
    2 km from center
    -
    Hassinger Daniels Guest House Hassinger Daniels Guest House
    Best by recreational activities
    1/1

    MAIN FEATURES

    • On-site karaoke and billiards provide fun and entertainment for guests.
    • Meeting and banquet facilities tailored for various events and gatherings.
    • Affordable pricing delivering unique recreational experiences not typical of hotels.
    Hassinger Daniels Guest House invites guests to experience unique recreational activities alongside restful accommodations. With on-site karaoke and billiards, it's perfect for both leisure and business travelers looking for a playful touch. Located conveniently near Birmingham attractions, it's stylishly suited for families seeking an engaging environment.

    Just a few rooms left at the best rate! 

    Variation not applicable

    Rates from verified hotel providers

Airport Hotels in Five Points South, Birmingham

  • 2 km from center
    -
    Best for historical charm

    MAIN FEATURES

    • Historical storytelling from the owner enhancing guest experiences.
    • Engaging communal dining space fostering connections among visitors.
    • Beautifully curated antique decor showcasing the hotel's character.
    Cobb Lane Bed and Breakfast invites travelers to indulge in charming Victorian comforts. This historic retreat offers personalized experiences, including home-cooked Southern breakfasts served in a vibrant communal atmosphere. Nestled within a beautifully landscaped garden, it's conveniently located near medical facilities and cultural attractions, making it perfect for leisure and business guests alike.
    $145-$207 per night

    Rates from verified hotel providers

Final Thoughts

Opting for the best hotels in Five Points South places you in one of Birmingham's most vibrant areas, conveniently located near the University of Alabama and the iconic Birmingham Zoo. These properties cater to various travelers, featuring unique amenities such as Southern-inspired cuisine at local bistros and spacious event facilities. With easy access to public transportation, this district ensures you can explore the city's culture and nightlife effortlessly.

Hotel options vary from boutique elegance to family-friendly suites, each providing distinct advantages. Enjoy engaging communal dining experiences and leisurely strolls to nearby parks and galleries. Investing in these accommodations guarantees a blend of comfort and practicality, setting you up for an unforgettable experience. Ready to enhance your Birmingham visit? Book your stay today.

Was this article helpful to you? Thanks for your feedback
10 min read
  • Why Stay in Five Points South?
  • Is Five Points South Safe?
  • Pet-friendly Hotels in Five Points South, Birmingham

    • 1. Hilton Birmingham Downtown At Uab
    • 2. Residence Inn By Marriott Birmingham Downtown Uab
    • 3. Home2 Suites By Hilton Birmingham Downtown
    • 4. Hilton Garden Inn Downtown Birmingham
    • 5. The Painted Lady
  • Luxury Accommodations in Five Points South, Birmingham

    • 6. Courtyard By Marriott Birmingham Downtown At Uab
    • 7. Hotel Indigo - Birmingham Five Points S - Uab By Ihg
    • 8. Springhill Suites By Marriott Birmingham Downtown At Uab
    • 9. Homewood Suites By Hilton Birmingham Downtown Near Uab
    • 10. Hassinger Daniels Guest House
  • Airport Hotels in Five Points South, Birmingham

    • 11. Cobb Lane Bed And Breakfast
  • Final Thoughts

You may also like

Explore more articles with curated hotel picks and local insights you might enjoy

Do you want to know more about Birmingham?

Show all articles
100% Verified Reviews
Select language
Currency
  • USD U.S. dollar
  • EUR Euro
  • GBP Pound sterling
  • AUD Australian dollar
  • CAD Canadian dollar
  • BRL Brazilian real
  • BGN Bulgarian lev
  • CNY Chinese yuan
  • CZK Czech koruna
  • DKK Danish krone
  • HKD Hong Kong dollar
  • ILS Israeli new sheqel
  • JPY Japanese yen
  • MYR Malaysian ringgit
  • NZD New Zealand dollar
  • NOK Norwegian krone
  • PLN Polish zloty
  • RON Romanian leu
  • RUB Russian ruble
  • SAR Saudi riyal
  • SGD Singapore dollar
  • ZAR South African rand
  • KRW South Korean won
  • SEK Swedish krona
  • CHF Swiss franc
  • TRY Turkish lira
  • UAH Ukrainian hryvnia
  • THB Thai baht
  • ARS Argentina, Peso
Contact Us
Birmingham hotels
Your details
Subject:
Message:
Your message has been sent
Your message was not delivered